Ralf Lesche

PTEN modulates cell cycle progression and cell survival by regulating phosphatidylinositol 3,4,5,-trisphosphate and Akt/protein kinase B signaling pathway

Hong Sun, Ralf Lesche, Daming Li et al. · Proceedings of the National Academy of Sciences · 1999 · 821 citations

Life Sciences, Cell Biology, Molecular Biology +17

Negative Regulation of Neural Stem/Progenitor Cell Proliferation by the <i>Pten</i> Tumor Suppressor Gene in Vivo

Matthias Groszer, Rebecca J. Erickson, Deirdre D. Scripture-Adams et al. · Science · 2001 · 792 citations · Full text

Life Sciences, Cell Biology, Neuroscience +17

PTEN tumor suppressor regulates p53 protein levels and activity through phosphatase-dependent and -independent mechanisms

Daniel J. Freeman, Andrew G. Li, Gang Wei et al. · Cancer Cell · 2003 · 515 citations · Full text

Life Sciences, Molecular Biology, Oncology +16

DNA Methylation Biomarkers for Blood-Based Colorectal Cancer Screening

Catherine Lofton–Day, Fabian Model, Theo deVos et al. · Clinical Chemistry · 2007 · 493 citations

Medicine, Molecular Biology, Oncology +17

Liver-specific deletion of negative regulator Pten results in fatty liver and insulin hypersensitivity

Bangyan L. Stiles, Ying Wang, Andreas Stahl et al. · Proceedings of the National Academy of Sciences · 2004 · 435 citations · Full text

Life Sciences, Endocrinology, Molecular Biology +17