Concepedia

Tetrahydropyridine-4-carboxamides as novel, potent transient receptor potential vanilloid 1 (TRPV1) antagonists

Brian S. Brown, Ryan G. Keddy, Guo Zhu Zheng, Robert G. Schmidt, John R. Koenig, Heath A. McDonald, Bruce R. Bianchi, Prisca Honoré, Michael F. Jarvis, Carol S. Surowy,

Bioorganic & Medicinal Chemistry · 2008 · 48 citations · 19 references

DOIFull text

Open access

Concepts

References

19

The capsaicin receptor: a heat-activated ion channel in the pain pathway

Michael J. Caterina, Mark Schumacher, Makoto Tominaga et al. · Nature · 1997 · 9.1K citations

, , +16

A new and sensitive method for measuring thermal nociception in cutaneous hyperalgesia

Kenneth Hargreaves, Ronald Dubner, Frederick J. Brown et al. · Pain · 1988 · 5.2K citations

, , +16

Impaired Nociception and Pain Sensation in Mice Lacking the Capsaicin Receptor

Michael J. Caterina, Andreas Leffler, Annika B. Malmberg et al. · Science · 2000 · 3.5K citations

, , +17

An experimental model for peripheral neuropathy produced by segmental spinal nerve ligation in the rat

Sun Ho Kim, Jin Mo Chung · Pain · 1992 · 3K citations

, , +17

Vanilloid receptor-1 is essential for inflammatory thermal hyperalgesia

John B. Davis, Julie Gray, Martin J. Gunthorpe et al. · Nature · 2000 · 1.8K citations

, , +14