Discovery of thienopyrimidine-based FLT3 inhibitors from the structural modification of known IKKβ inhibitors

NF-κB is activated and promotes cell death in focal cerebral ischemia

Armin Schneider, Ana Martín-Villalba, Falk Weih et al. · Nature Medicine · 1999 · 648 citations

Life Sciences, Neurology, Neuroscience +12

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

S Yokota, Hitoshi Kiyoi, Makoto Nakao et al. · Leukemia · 1997 · 458 citations

Life Sciences, Genetics, Hematology +17

Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NFκB-dependent mechanism

Keith T. Akama, Chris Albanese, Richard G. Pestell et al. · Proceedings of the National Academy of Sciences · 1998 · 348 citations

Life Sciences, Neurobiology, Neuroscience +17

Essential Role of Nuclear Factor κB in the Induction of Eosinophilia in Allergic Airway Inflammation

Liyan Yang, Lauren Cohn, Dong-Hong Zhang et al. · The Journal of Experimental Medicine · 1998 · 306 citations · Full text

Life Sciences, Immunology, Molecular Biology +15

Biologic and clinical significance of the FLT3 transcript level in acute myeloid leukemia

K. Ozeki · Blood · 2003 · 275 citations

Medicine, Molecular Biology, Oncology +16