Keith T. Akama

β-Amyloid Stimulation of Inducible Nitric-oxide Synthase in Astrocytes Is Interleukin-1β- and Tumor Necrosis Factor-α (TNFα)-dependent, and Involves a TNFα Receptor-associated Factor- and NFκB-inducing Kinase-dependent Signaling Mechanism

Keith T. Akama, Linda J. Van Eldik · Journal of Biological Chemistry · 2000 · 360 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Amyloid β-peptide stimulates nitric oxide production in astrocytes through an NFκB-dependent mechanism

Keith T. Akama, Chris Albanese, Richard G. Pestell et al. · Proceedings of the National Academy of Sciences · 1998 · 348 citations

Life Sciences, Neurobiology, Neuroscience +17

Amyloid-β peptide activates cultured astrocytes: morphological alterations, cytokine induction and nitric oxide release

Jingru Hu, Keith T. Akama, Grant A. Krafft et al. · Brain Research · 1998 · 315 citations

Medicine, Neurobiology, Neuroscience +17

Cyclopentenone prostaglandins suppress activation of microglia: Down-regulation of inducible nitric-oxide synthase by 15-deoxy-Δ ^12,14 -prostaglandin J ₂

Tatiana V. Petrova, Keith T. Akama, Linda J. Van Eldik · Proceedings of the National Academy of Sciences · 1999 · 314 citations

Medicine, Neurobiology, Neuroscience +17

Cerebrospinal fluid S100B is elevated in the earlier stages of Alzheimer's disease

Elaine R. Peskind, W. Sue T. Griffin, Keith T. Akama et al. · Neurochemistry International · 2001 · 213 citations

Life Sciences, Neurology, Neuroscience +13