Hitoshi Kiyoi

Prognostic implication of FLT3 and N-RAS gene mutations in acute myeloid leukemia.

Hitoshi Kiyoi, Tomoki Naoe, Yasuyuki Nakano et al. · PubMed · 1999 · 765 citations

Tandem-duplicated Flt3 constitutively activates STAT5 and MAP kinase and introduces autonomous cell growth in IL-3-dependent cell lines

Fumihiko Hayakawa, Masayuki Towatari, Hitoshi Kiyoi et al. · Oncogene · 2000 · 559 citations

Signal Transduction, Signaling Pathway, Cell Regulation +9

Internal tandem duplication of the FLT3 gene is preferentially seen in acute myeloid leukemia and myelodysplastic syndrome among various hematological malignancies. A study on a large series of patients and cell lines

S Yokota, Hitoshi Kiyoi, Makoto Nakao et al. · Leukemia · 1997 · 454 citations

Hematological Malignancy, Chromatin, Flt3 Gene +10

Internal tandem duplication of the FLT3 gene is a novel modality of elongation mutation which causes constitutive activation of the product

Hitoshi Kiyoi, Masayuki Towatari, Shohei Yokota et al. · Leukemia · 1998 · 446 citations

Flt3 Gene, Developmental Biology, Genetic Disorder +8

Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma

Kazuhito Yamamoto, Atae Utsunomiya, Kensei Tobinai et al. · Journal of Clinical Oncology · 2010 · 350 citations · Full text