Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma - Concepedia

Concepedia

Publication | Open Access

Phase I Study of KW-0761, a Defucosylated Humanized Anti-CCR4 Antibody, in Relapsed Patients With Adult T-Cell Leukemia-Lymphoma and Peripheral T-Cell Lymphoma

DOI Full Paper Access

350

Citations

33

References

2010

Year

Kazuhito Yamamoto, Atae Utsunomiya, Kensei Tobinai, Kunihiro Tsukasaki, Naokuni Uike, Kimiharu Uozumi, Kazunari Yamaguchi, Yasuaki Yamada, Shuichi Hanada, Kazuo Tamura,

Journal of Clinical Oncology

Abstract

KW-0761 was tolerated at all the dose levels tested, demonstrating potential efficacy against relapsed CCR4-positive ATL or PTCL. Subsequent phase II studies at the 1.0 mg/kg dose are thus warranted.

References

	Year	Citations

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