Impairment of bunitrolol 4-hydroxylase activity in liver microsomes of Dark Agouti rats

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

Life Sciences, Biochemistry, Chemistry +8

A pharmacokinetic analysis program (multi) for microcomputer.

Kiyoshi Yamaoka, Yusuke Tanigawara, Terumichi Nakagawa et al. · Journal of Pharmacobio-Dynamics · 1981 · 2.5K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +12

Hormonal regulation of rat liver microsomal enzymes. Role of gonadal steroids in programming, maintenance, and suppression of delta 4-steroid 5 alpha-reductase, flavin-containing monooxygenase, and sex-specific cytochromes P-450.

Ghazi A. Dannan, F. Peter Guengerich, David J. Waxman · Journal of Biological Chemistry · 1986 · 167 citations · Full text

Life Sciences, Biochemistry, Endocrinology +17

Purification and characterization of the rat liver microsomal cytochrome P-450 involved in the 4-hydroxylation of debrisoquine, a prototype for genetic variation in oxidative drug metabolism

Dominique Larrey, Linda M. Distlerath, Ghazi A. Dannan et al. · Biochemistry · 1984 · 150 citations

Medicine, Biochemistry, Pharmacology +15

Animal modelling of human polymorphic drug oxidation—the metabolism of debrisoquine and phenacetin in rat inbred strains

Sabah G. Al-Dabbagh, Jeffrey R. Idle, Richard L. Smith · Journal of Pharmacy and Pharmacology · 1981 · 141 citations

Medicine, Pharmacology, Toxicology +11