Shin Umeda

<b><i>In vitro</i></b>drug–drug interaction studies with febuxostat, a novel non-purine selective inhibitor of xanthine oxidase: plasma protein binding, identification of metabolic enzymes and cytochrome P450 inhibition

M. Mukoyoshi, Shinichi Nishimura, S. Hoshide et al. · Xenobiotica · 2008 · 58 citations

Medicine, Pharmacokinetics, Pharmacology +17

Diaphanous gene mutation affects spiral cleavage and chirality in snails

Reiko Kuroda, Kohei Fujikura, Masanori Abe et al. · Scientific Reports · 2016 · 49 citations · Full text

Life Sciences, Biology, Genetics +17

Purification and characterization of a cytochrome P-450 isozyme catalyzing bunitrolol 4-hydroxylation in liver microsomes of male rats.

Toshikazu Suzuki, S. Narimatsu, S. Fujita et al. · Drug Metabolism and Disposition · 1992 · 34 citations

Life Sciences, Biochemistry, Pharmacology +16

Regio- and stereoselective propranolol metabolism by 15 forms of purified cytochromes P-450 from rat liver.

S. Fujita, Shin Umeda, Yoshihiko Funae et al. · Journal of Pharmacology and Experimental Therapeutics · 1993 · 24 citations

Medicine, Biochemistry, Pharmacology +17

Impairment of bunitrolol 4-hydroxylase activity in liver microsomes of Dark Agouti rats

Tokuji Suzuki, Shizuo Narimatsu, Shoichi Fujita et al. · Biochemical Pharmacology · 1991 · 19 citations

Medicine, Biochemistry, Pharmacology +15