Concepedia

A DNA-Damage Selective Role for BRCA1 E3 Ligase in Claspin Ubiquitylation, CHK1 Activation, and DNA Repair

Ko Sato, Elayanambi Sundaramoorthy, Eeson Rajendra, Hiroyoshi Hattori, Anand D. Jeyasekharan, Nabieh Ayoub, Ralph Schiess, Ruedi Aebersold, Hiroyuki Nishikawa, Anna S. Sedukhina,

Current Biology · 2012 · 66 citations · 30 references

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Chk1 is an essential kinase that is regulated by Atr and required for the G<sub>2</sub>/M DNA damage checkpoint

Qinghua Liu, Saritha Guntuku, Xian-Shu Cui et al. · Genes & Development · 2000 · 1.6K citations · Full text

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ATR-Mediated Checkpoint Pathways Regulate Phosphorylation and Activation of Human Chk1

Hui Zhao, Helen Piwnica‐Worms · Molecular and Cellular Biology · 2001 · 1.1K citations · Full text

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A uniform proteomics MS/MS analysis platform utilizing open XML file formats

Andrew Keller, Jimmy K. Eng, Ning Zhang et al. · Molecular Systems Biology · 2005 · 714 citations

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The cell-cycle checkpoint kinase Chk1 is required for mammalian homologous recombination repair

Claus Storgaard Sørensen, Lasse Tengbjerg Hansen, Jaroslaw Dziegielewski et al. · Nature Cell Biology · 2005 · 648 citations

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The RING Heterodimer BRCA1-BARD1 Is a Ubiquitin Ligase Inactivated by a Breast Cancer-derived Mutation

Rintaro Hashizume, Mamoru Fukuda, Ichiro Maeda et al. · Journal of Biological Chemistry · 2001 · 638 citations · Full text

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