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MedicineGeneticsOncologyCarcinogenesisDna RepairMolecular OncologyCancer Molecular PathologyDna Damage-induced ApoptosisMalignant NeoplasmsMolecular Tumor ProfilingSquamous Cell CarcinomaP53 AbnormalityP53 InactivationP53 MutationP53 Pathway InactivationP53 Protein ResponseP53-mediated ApoptosisTp53 MutationsTumor Suppressor P53
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Genetic Alterations during Colorectal-Tumor Development
Bert Vogelstein, Eric R. Fearon, Stanley R. Hamilton et al. · New England Journal of Medicine · 1988 · 6.8K citations
Mice deficient for p53 are developmentally normal but susceptible to spontaneous tumours
Lawrence A. Donehower, Michele Harvey, Betty L. Slagle et al. · Nature · 1992 · 4.7K citations
Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms
David Malkin, Frederick P. Li, Louise C. Strong et al. · Science · 1990 · 3.8K citations
Life Sciences, Genetics, Oncology +17