David Malkin

Germ Line p53 Mutations in a Familial Syndrome of Breast Cancer, Sarcomas, and Other Neoplasms

David Malkin, Frederick P. Li, Louise C. Strong et al. · Science · 1990 · 3.8K citations

Breast Oncology, Genetics, Genetic Epidemiology +16

Driver mutations in histone H3.3 and chromatin remodelling genes in paediatric glioblastoma

Jeremy Schwartzentruber, Andrey Korshunov, Xiao-Yang Liu et al. · Nature · 2012 · 2.6K citations

Chromatin, Neuro-oncology, Chromatin Structure +13

Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations

Tobias Rausch, David Jones, Marc Zapatka et al. · Cell · 2012 · 857 citations · Full text

Dna Sequencing, Somatic Variant, Tumor Heterogeneity +8

Immune Checkpoint Inhibition for Hypermutant Glioblastoma Multiforme Resulting From Germline Biallelic Mismatch Repair Deficiency

Éric Bouffet, Valérie Larouche, Brittany Campbell et al. · Journal of Clinical Oncology · 2016 · 847 citations

Comprehensive Analysis of Hypermutation in Human Cancer

Brittany Campbell, Nicholas Light, David Fabrizio et al. · Cell · 2017 · 772 citations · Full text

Somatic Variant, Cancer Genomics, Comprehensive Analysis +5