A Role for the MRN Complex in ATR Activation via TOPBP1 Recruitment

Sensing DNA Damage Through ATRIP Recognition of RPA-ssDNA Complexes

Lee Zou, Stephen J. Elledge · Science · 2003 · 2.6K citations

ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks

Ali Jazayeri, Jacob Falck, Claudia Lukas et al. · Nature Cell Biology · 2005 · 1K citations

Chromatin, Genome Instability, Transcriptional Regulation +13

Functional uncoupling of MCM helicase and DNA polymerase activities activates the ATR-dependent checkpoint

Tony Byun, Marcin Pacek, Muh‐Ching Yee et al. · Genes & Development · 2005 · 747 citations · Full text

TopBP1 Activates the ATR-ATRIP Complex

Akiko Kumagai, Joon Lee, Hae Yong Yoo et al. · Cell · 2006 · 716 citations · Full text

Signal Transduction, Atr-atrip Complex, Molecular Biology +3

The Rad9–Hus1–Rad1 (9–1–1) clamp activates checkpoint signaling via TopBP1

Sinny Delacroix, Jill M. Wagner, Masahiko Kobayashi et al. · Genes & Development · 2007 · 457 citations · Full text