Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

Overexpression of a Transporter Gene in a Multidrug-Resistant Human Lung Cancer Cell Line

Susan P.C. Cole, Gabu Bhardwaj, James H. Gerlach et al. · Science · 1992 · 3.1K citations

Medicine, Molecular Biology, Oncology +16

Functional polymorphisms of the human multidrug-resistance gene: Multiple sequence variations and correlation of one allele with P-glycoprotein expression and activity <i>in</i> <i>vivo</i>

Sven Hoffmeyer, Oliver Burk, Oliver von Richter et al. · Proceedings of the National Academy of Sciences · 2000 · 2.4K citations

Medicine, Molecular Genetics, Pharmacology +15

P-glycoprotein in the blood-brain barrier of mice influences the brain penetration and pharmacological activity of many drugs.

Alfred H. Schinkel, Els Wagenaar, Carla A.A.M. Mol et al. · Journal of Clinical Investigation · 1996 · 1.3K citations · Full text

Medicine, Pharmacokinetics, Pharmacology +15

Fusion Between Transcription Factor CBFβ/PEBP2β and a Myosin Heavy Chain in Acute Myeloid Leukemia

Pu Liu, Susan A. Tarlé, A K Hajra et al. · Science · 1993 · 743 citations

Life Sciences, Genetics, Molecular Genetics +12

A mutation in the human canalicular multispecific organic anion transporter gene causes the Dubin-Johnson syndrome

Coen C. Paulusma, Marcel Kool, Piter J. Bosma et al. · Hepatology · 1997 · 557 citations · Full text

Medicine, Genetics, Molecular Genetics +17