Kenji Otsubo

Expression of P-glycoprotein in Human Placenta: Relation to Genetic Polymorphism of the Multidrug Resistance (MDR)-1 Gene

Mizuho Tanabe, Ichiro Ieiri, Naoki Nagata et al. · Journal of Pharmacology and Experimental Therapeutics · 2001 · 535 citations

Life Sciences, Genetics, Molecular Genetics +13

Different contributions of polymorphisms in VKORC1 and CYP2C9 to intra- and inter-population differences in maintenance dose of warfarin in Japanese, Caucasians and African-Americans

Harumi Takahashi, G. Wilkinson, Edith A. Nutescu et al. · Pharmacogenetics and Genomics · 2006 · 374 citations · Full text

Medicine, Pharmacokinetics, Pharmacology +16

FUNCTIONAL ASSESSMENT OF ABCG2 (BCRP) GENE POLYMORPHISMS TO PROTEIN EXPRESSION IN HUMAN PLACENTA

Daisuke Kobayashi, Ichiro Ieiri, Takeshi Hirota et al. · Drug Metabolism and Disposition · 2004 · 271 citations

Life Sciences, Genetics, Molecular Genetics +13

Role of human <i>MDR1</i> gene polymorphism in bioavailability and interaction of digoxin, a substrate of P‐glycoprotein

Yasuo Kurata, Ichiro Ieiri, Miyuki Kimura et al. · Clinical Pharmacology & Therapeutics · 2002 · 269 citations

Pharmacy, Pharmacokinetics, Pharmacology +9

Polymorphism of the ABC transporter genes, MDR1, MRP1 and MRP2/cMOAT, in healthy Japanese subjects

Soichiro Ito, Ichiro Ieiri, Mizuho Tanabe et al. · Pharmacogenetics · 2001 · 235 citations

Life Sciences, Genetics, Molecular Genetics +11