Concepedia

Publication | Closed Access

Role of human <i>MDR1</i> gene polymorphism in bioavailability and interaction of digoxin, a substrate of P‐glycoprotein

DOI

268

Citations

0

References

2002

Year

Yasuo Kurata, Ichiro Ieiri, Miyuki Kimura, Toshihiro Morita, Shin Irie, Akinori Urae, Shigehiro Ohdo, Hisakazu Ohtani, Yasufumi Sawada, Shun Higuchi,
Clinical Pharmacology & Therapeutics

Abstract

The allelic variants in the human MDR1 gene are likely to be associated with altered absorption and/or disposition profiles of digoxin and P-glycoprotein-mediated drug interaction