Valproic Acid Alleviates Memory Deficits and Attenuates Amyloid-β Deposition in Transgenic Mouse Model of Alzheimer’s Disease

Place navigation impaired in rats with hippocampal lesions

Richard Morris, Paul Garrud, J. N. P. Rawlins et al. · Nature · 1982 · 6.4K citations

Life Sciences, Neurobiology, Neuroscience +14

Intraneuronal β-Amyloid Aggregates, Neurodegeneration, and Neuron Loss in Transgenic Mice with Five Familial Alzheimer's Disease Mutations: Potential Factors in Amyloid Plaque Formation

Holly D. Oakley, Sarah L. Cole, Sreemathi Logan et al. · Journal of Neuroscience · 2006 · 3.6K citations · Full text

Life Sciences, Neurology, Neuroscience +17

The NALP3 inflammasome is involved in the innate immune response to amyloid-β

Annett Halle, Veit Hornung, Gabor C. Petzold et al. · Nature Immunology · 2008 · 2.4K citations · Full text

Life Sciences, Cell Biology, Immunology +13

Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC

Shigeomi Shimizu, Masashi Narita, Yoshihide Tsujimoto et al. · Nature · 1999 · 2.2K citations

Life Sciences, Biochemistry, Molecular Biology +10

Decreased nuclear β‐catenin, tau hyperphosphorylation and neurodegeneration in GSK‐3β conditional transgenic mice

José J. Lucas · The EMBO Journal · 2001 · 898 citations · Full text

Life Sciences, Molecular Biology, Neuroscience +13