Concepedia

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

Yizhe Tang, Izumi Horikawa, Masahiko Ajiro, Ana I. Robles, Kaori Fujita, Amit Mondal, Jimmy K. Stauffer, Curtis C. Harris

Oncogene · 2012 · 160 citations · 66 references

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66

The limited in vitro lifetime of human diploid cell strains

Leonard Hayflick · Experimental Cell Research · 1965 · 5.8K citations

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Alternative isoform regulation in human tissue transcriptomes

Eric T. Wang, Rickard Sandberg, Shujun Luo et al. · Nature · 2008 · 5.4K citations · Full text

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Oncogenic ras Provokes Premature Cell Senescence Associated with Accumulation of p53 and p16INK4a

Manuel Serrano, Athena W. Lin, Mila E. McCurrach et al. · Cell · 1997 · 5.1K citations · Full text

, , +10

Tumorigenic conversion of primary embryo fibroblasts requires at least two cooperating oncogenes

Hartmut Land, Luis F. Parada, Robert A. Weinberg · Nature · 1983 · 2.9K citations

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The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth

Heather R. Christofk, Matthew G. Vander Heiden, Marian H. Harris et al. · Nature · 2008 · 2.8K citations

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