Yizhe Tang

Hypothalamic programming of systemic ageing involving IKK-β, NF-κB and GnRH

Guo Zhang, Juxue Li, Sudarshana Purkayastha et al. · Nature · 2013 · 810 citations · Full text

Aging, Stress Hormone, Physiology +6

IKKβ/NF-κB disrupts adult hypothalamic neural stem cells to mediate a neurodegenerative mechanism of dietary obesity and pre-diabetes

Juxue Li, Yizhe Tang, Dongsheng Cai · Nature Cell Biology · 2012 · 342 citations · Full text

Obesity, Metabolic Syndrome, Neurodegenerative Diseases +12

Downregulation of splicing factor SRSF3 induces p53β, an alternatively spliced isoform of p53 that promotes cellular senescence

Yizhe Tang, Izumi Horikawa, Masahiko Ajiro et al. · Oncogene · 2012 · 154 citations · Full text

Cell Regulation, Spliced Isoform, Cellular Senescence +4

Obesity- and aging-induced excess of central transforming growth factor-β potentiates diabetic development via an RNA stress response

Jingqi Yan, Hai Zhang, Ye Yin et al. · Nature Medicine · 2014 · 142 citations · Full text

Obesity, Metabolic Syndrome, Systems Biology +9

Directing adenovirus across the blood–brain barrier via melanotransferrin (P97) transcytosis pathway in an in vitro model

Yizhe Tang, Tian Han, Maaike Everts et al. · Gene Therapy · 2006 · 46 citations

Blood–brain Barrier, Vitro Model, Immunology +10