Phosphorylation of Bim-EL by Erk1/2 on serine 69 promotes its degradation via the proteasome pathway and regulates its proapoptotic function

Single-step purification of polypeptides expressed in Escherichia coli as fusions with glutathione S-transferase

Donald B. Smith, Kevin S. Johnson · Gene · 1988 · 6K citations

Life Sciences, Biochemistry, Molecular Biology +12

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +16

Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis

Zhengui Xia, Martin Dickens, Joël Raingeaud et al. · Science · 1995 · 5.3K citations

Life Sciences, Neurobiology, Neuroscience +16

Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL

Jiping Zha, Hisashi Harada, Elizabeth Yang et al. · Cell · 1996 · 2.6K citations · Full text

Life Sciences, Cell Biology, Apoptosis +15

Cell Survival Promoted by the Ras-MAPK Signaling Pathway by Transcription-Dependent and -Independent Mechanisms

Azad Bonni, Anne Brunet, Anne E. West et al. · Science · 1999 · 1.9K citations

Life Sciences, Cell Biology, Neuroscience +17