Deletion of the Telomerase Reverse Transcriptase Gene and Haploinsufficiency of Telomere Maintenance in Cri du Chat Syndrome

A biomarker that identifies senescent human cells in culture and in aging skin in vivo.

Goberdhan P. Dimri, X Lee, George Basile et al. · Proceedings of the National Academy of Sciences · 1995 · 7.3K citations · Full text

Replicative Senescence, Developmental Biology, Aging +14

Telomeres shorten during ageing of human fibroblasts

Calvin B. Harley, A. B. Futcher, Carol W. Greider · Nature · 1990 · 5.6K citations

Fibrosis, Aging, Longevity +4

Extension of Life-Span by Introduction of Telomerase into Normal Human Cells

Andrea Bodnár, Michel Ouellette, Maria Frolkis et al. · Science · 1998 · 4.9K citations

Creation of human tumour cells with defined genetic elements

William C. Hahn, Christopher M. Counter, Ante S. Lundberg et al. · Nature · 1999 · 2.3K citations

Tumor Biology, Human Cell, Tumor Heterogeneity +6

Telomerase Catalytic Subunit Homologs from Fission Yeast and Human

Toru Nakamura, Gregg B. Morin, Karen Chapman et al. · Science · 1997 · 2.3K citations · Full text

Catalytic Protein Subunits, Chromatin, Telomerase Catalytic Subunits +13