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Sensitive determination of irinotecan (CPT-11) and its active metabolite SN-38 in human serum using liquid chromatography–electrospray mass spectrometry

Pharmaceutical ScienceBiochemistryGas ChromatographyMedicineBioanalysisMass SpectrometryActive Metabolite Sn-38Metabolomic ProfilingChemical PathologyAnalytical ChemistrySensitive DeterminationClinical ChemistryHuman SerumLiquid ChromatographyPharmacologyChromatographyDrug Analysis