Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans - Concepedia

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Novel Antiplatelet Drug Revacept (Dimeric Glycoprotein VI-Fc) Specifically and Efficiently Inhibited Collagen-Induced Platelet Aggregation Without Affecting General Hemostasis in Humans

237

Citations

25

References

2011

Year

Martin Ungerer, Kai Rosport, Andreas Bültmann, Richard Piechatzek, Kerstin Uhland, Peter Schlieper, Meinrad Gawaz, Götz Münch

Abstract

URL: www.clinicaltrials.gov. Unique identifier: NCT 01042964. URL: eudract.ema.europa.eu. Identifier: 2005-004656-12.

References

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A Crucial Role of Glycoprotein VI for Platelet Recruitment to the Injured Arterial Wall In Vivo Meinrad Gawaz, Sabine Grüner, Valerie Schulte, The Journal of Experimental Medicine Vascular DiseaseImmunologyGlycoprotein ViBiomedical EngineeringInflammation	2002	504
A patient with platelets deficient in glycoprotein VI that lack both collagen-induced aggregation and adhesion. Masaaki Moroi, Stéphanie Jung, M Okuma, Journal of Clinical Investigation Collagen ReceptorImmunologyGlycoprotein ViPathologyInflammation	1989	464
Long-Term Antithrombotic Protection by in Vivo Depletion of Platelet Glycoprotein VI in Mice Bernhard Nieswandt, Valerie Schulte, Wolfgang Bergmeier, The Journal of Experimental Medicine	2001	348
Loading With 600 mg Clopidogrel in Patients With Coronary Artery Disease With and Without Chronic Clopidogrel Therapy Adnan Kastrati, Nicolas von Beckerath, Alexander Joost, Circulation	2004	195
Soluble glycoprotein VI dimer inhibits platelet adhesion and aggregation to the injured vessel wall in vivo Ildiko Konrad, Andreas Bültmann, Christian Schulz, The FASEB Journal	2003	194
A 2-Step Mechanism of Arterial Thrombus Formation Induced by Human Atherosclerotic Plaques Armin J. Reininger, Isabell Bernlochner, Sandra Penz, Journal of the American College of Cardiology ThrombosisVascular DiseaseCardiovascular DiseaseBlood PlateletPhysiology	2010	183
Human atheromatous plaques stimulate thrombus formation by activating platelet glycoprotein VI Sandra Penz, Armin J. Reininger, Richard Brandl, The FASEB Journal Vascular DiseaseImmunologyPathologyPlatelet Collagen ReceptorInflammation	2005	161
Platelet Glycoprotein IIb/IIIa Inhibitors Martin Quinn, Edward F. Plow, Eric J. Topol Circulation ThrombopoiesisThrombosisPlatelet Aggregation InhibitorsMolecular PharmacologyBlood Platelet	2002	160

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