TNF-α Stimulation of MCP-1 Expression Is Mediated by the Akt/PKB Signal Transduction Pathway in Vascular Endothelial Cells

Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery

Sandeep Robert Datta, Henryk Dudek, Xu Tao et al. · Cell · 1997 · 5.7K citations · Full text

Signal Transduction, Signaling Pathway, Cell Regulation +11

Activation of nitric oxide synthase in endothelial cells by Akt-dependent phosphorylation

Stefanie Dimmeler, Ingrid Fleming, Beate Fißlthaler et al. · Nature · 1999 · 3.6K citations

Endothelial Cells, Cellular Physiology, Oxidative Stress +17

NF-κB activation by tumour necrosis factor requires the Akt serine–threonine kinase

Osman Nidai Özeş, Lindsey D. Mayo, Jason A. Gustin et al. · Nature · 1999 · 2.2K citations

Inflammation, Cytokine, Tumour Necrosis Factor +15

The protein kinase encoded by the Akt proto-oncogene is a target of the PDGF-activated phosphatidylinositol 3-kinase

Thomas Franke, Sung‐Il Yang, Tung O. Chan et al. · Cell · 1995 · 2K citations · Full text

Akt Proto-oncogene, Signal Transduction, Signaling Pathway +11

A Retroviral Oncogene, <i>akt</i> , Encoding a Serine-Threonine Kinase Containing an SH2-Like Region

Alfonso Bellacosa, Joseph R. Testa, Stephen Staal et al. · Science · 1991 · 885 citations