Concepedia

C6 ceramide sensitizes pemetrexed-induced apoptosis and cytotoxicity in osteosarcoma cells

Xinhui Zhu, Xueping Du, Xiaolong Deng, Hong Yi, Shengyu Cui, Wei Liu, Aiguo Shen, Zhiming Cui

Biochemical and Biophysical Research Communications · 2014 · 12 citations · 26 references

DOI

Concepts

References

26

Ceramide activates heterotrimeric protein phosphatase 2A

Rick T. Dobrowsky, Craig Kamibayashi, Marc C. Mumby et al. · Journal of Biological Chemistry · 1993 · 663 citations · Full text

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Role of ceramide-activated protein phosphatase in ceramide-mediated signal transduction.

Robert A. Wolff, Rick T. Dobrowsky, Alicja Bielawska et al. · Journal of Biological Chemistry · 1994 · 287 citations · Full text

, , +17

Phosphorylation by Akt1 promotes cytoplasmic localization of Skp2 and impairs APCCdh1-mediated Skp2 destruction

Daming Gao, Hiroyuki Inuzuka, Alan Tseng et al. · Nature Cell Biology · 2009 · 279 citations · Full text

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Schedule-Dependent Cytotoxic Synergism of Pemetrexed and Erlotinib in Human Non–Small Cell Lung Cancer Cells

Tianhong Li, Yi‐He Ling, I. David Goldman et al. · Clinical Cancer Research · 2007 · 218 citations · Full text

, , +17

Blockage of Epidermal Growth Factor Receptor-Phosphatidylinositol 3-Kinase-AKT Signaling Increases Radiosensitivity of K-<i>RAS</i> Mutated Human Tumor Cells <i>In vitro</i> by Affecting DNA Repair

Mahmoud Toulany, Ulla Kasten-Pisula, Shaomeng Wang et al. · Clinical Cancer Research · 2006 · 208 citations

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