Concepedia

Quinazolinecarboline alkaloid evodiamine as scaffold for targeting topoisomerase I and sirtuins

Michael S. Christodoulou, Alessandro Sacchetti, Valentina Ronchetti, Stefania Caufin, Alessandra Silvani, Giordano Lesma, Gabriele Fontana, Fabrizio Minicone, Benedetta Riva, Micol Ventura,

Bioorganic & Medicinal Chemistry · 2013 · 32 citations · 48 references

DOI

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References

48

Discovery of Indoles as Potent and Selective Inhibitors of the Deacetylase SIRT1

Andrew D. Napper, Jeffrey Hixon, Thomas McDonagh et al. · Journal of Medicinal Chemistry · 2005 · 525 citations · Full text

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Discovery of Thieno[3,2-<i>d</i>]pyrimidine-6-carboxamides as Potent Inhibitors of SIRT1, SIRT2, and SIRT3

Jeremy S. Disch, Ghotas Evindar, Cynthia H. Chiu et al. · Journal of Medicinal Chemistry · 2013 · 197 citations · Full text

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New Tricks for an Old Natural Product: Discovery of Highly Potent Evodiamine Derivatives as Novel Antitumor Agents by Systemic Structure–Activity Relationship Analysis and Biological Evaluations

Guoqiang Dong, Shengzheng Wang, Zhenyuan Miao et al. · Journal of Medicinal Chemistry · 2012 · 185 citations

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Capsaicin-Like Anti-Obese Activities of Evodiamine from Fruits of Evodia rutaecarpa, a Vanilloid Receptor Agonist

Yoshinori Kobayashi, Yumiko Nakano, Miho Kizaki et al. · Planta Medica · 2001 · 175 citations

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Selection of Evodiamine as a Novel Topoisomerase I Inhibitor by Structure-Based Virtual Screening and Hit Optimization of Evodiamine Derivatives as Antitumor Agents

Guoqiang Dong, Chunquan Sheng, Shengzheng Wang et al. · Journal of Medicinal Chemistry · 2010 · 150 citations

, , +17