Concepedia

Modulation of constitutive androstane receptor (CAR) and pregnane X receptor (PXR) by 6-arylpyrrolo[2,1-d][1,5]benzothiazepine derivatives, ligands of peripheral benzodiazepine receptor (PBR)

Linnea E. Anderson, Ann M. Dring, Matthew Stoner

Toxicology Letters · 2011 · 20 citations · 27 references

DOIFull text

Open access

Concepts

References

27

An Orphan Nuclear Receptor Activated by Pregnanes Defines a Novel Steroid Signaling Pathway

Steven A. Kliewer, John T. Moore, Laura Wade et al. · Cell · 1998 · 1.5K citations · Full text

, , +16

SXR, a novel steroid and xenobioticsensing nuclear receptor

Bruce Blumberg, Walid Sabbagh, Henry Juguilon et al. · Genes & Development · 1998 · 920 citations · Full text

, , +17

Orphan Nuclear Receptors Constitutive Androstane Receptor and Pregnane X Receptor Share Xenobiotic and Steroid Ligands

Linda B. Moore, Derek J. Parks, Stacey A. Jones et al. · Journal of Biological Chemistry · 2000 · 810 citations · Full text

, , +17

The Nuclear Orphan Receptor CAR-Retinoid X Receptor Heterodimer Activates the Phenobarbital-Responsive Enhancer Module of the <i>CYP2B</i> Gene

Paavo Honkakoski, Igor N. Zelko, Tatsuya Sueyoshi et al. · Molecular and Cellular Biology · 1998 · 705 citations

, , +17

The Orphan Human Pregnane X Receptor Mediates the Transcriptional Activation of<i>CYP3A4</i>by Rifampicin through a Distal Enhancer Module

Bryan Goodwin, Ecushla Hodgson, Christopher Liddle · Molecular Pharmacology · 1999 · 643 citations

, , +17