Interaction of the DNA topoisomerase II catalytic inhibitor meso-2,3-bis(3,5-dioxopiperazine-1-yl)butane (ICRF-193), a bisdioxopiperazine derivative, with the conserved region(s) of eukaryotic but not prokaryotic enzyme

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Antitumor bisdioxopiperazines inhibit yeast DNAtopoisomerase II by trapping the enzyme in the form of a closed proteinclamp. Joaquím Roca, Ryoji Ishida, James M. Berger, Proceedings of the National Academy of Sciences Molecular BiologyAntimicrobial ChemotherapyType Ii DnaChemical BiologyDrug Resistance	1994	351
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T4 DNA topoisomerase: a new ATP-dependent enzyme essential for initiation of T4 bacteriophage DNA replication Leroy F. Liu, Chung-Cheng Liu, Bruce Alberts Nature New Atp-dependent EnzymeT4 Dna TopoisomeraseNatural SciencesBacteriophageDna Replication	1979	268
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Topoisomerase II does not play a scaffolding role in the organization of mitotic chromosomes assembled in Xenopus egg extracts. Tatsuya Hirano, Timothy J. Mitchison The Journal of Cell Biology CytogeneticsGeneticsMolecular BiologyMolecular GeneticsReproductive Biology	1993	233
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