The discovery of glycine and related amino acid-based factor Xa inhibitors

Molecular Properties That Influence the Oral Bioavailability of Drug Candidates

Daniel F. Veber, Stephen R. Johnson, Hung‐Yuan Cheng et al. · Journal of Medicinal Chemistry · 2002 · 7.8K citations

Medicinal Chemistry, Oral Bioavailability, Pharmaceutical Science +13

Discovery of the Novel Antithrombotic Agent 5-Chloro-<i>N</i>-({(5<i>S</i>)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939):  An Oral, Direct Factor Xa Inhibitor

Susanne Roehrig, Alexander Straub, Jens Pohlmann et al. · Journal of Medicinal Chemistry · 2005 · 429 citations · Full text

Pharmacotherapy, Chemical Biology, Pharmaceutical Chemistry +17

Structures of polypeptides from α-amino acids disubstituted at the α-carbon

Claudio Toniolo, Ettore Benedetti · Macromolecules · 1991 · 420 citations

Bioorganic Chemistry, Databases, Altmetric Attention Score +22

Assay of heparin in plasma using a chromogenic substrate for activated factor X

Arne N. Teien, Ulrich Abildgaard · Thrombosis Research · 1976 · 297 citations

Thrombopoiesis, Chromogenic Substrate, Biochemistry +11

Evaluation of an amidolytic heparin assay method: Increased sensitivity by adding purified antithrombin III

Arne N. Teien · Thrombosis Research · 1977 · 291 citations

Thrombopoiesis, Thrombosis, Purified Antithrombin Iii +13