Alexander Straub

NO-independent regulatory site on soluble guanylate cyclase

Johannes-Peter Stasch, Eva Maria Becker, Cristina Alonso‐Alija et al. · Nature · 2001 · 544 citations

Life Sciences, Biochemistry, Molecular Biology +9

Discovery of the Novel Antithrombotic Agent 5-Chloro-<i>N</i>-({(5<i>S</i>)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939):  An Oral, Direct Factor Xa Inhibitor

Susanne Roehrig, Alexander Straub, Jens Pohlmann et al. · Journal of Medicinal Chemistry · 2005 · 433 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Discovery of the Soluble Guanylate Cyclase Stimulator Vericiguat (BAY 1021189) for the Treatment of Chronic Heart Failure

Markus Follmann, Jens Ackerstaff, Gorden Redlich et al. · Journal of Medicinal Chemistry · 2017 · 197 citations · Full text

Medicine, Cardiology, Pharmacology +17

Discovery of Riociguat (BAY 63‐2521): A Potent, Oral Stimulator of Soluble Guanylate Cyclase for the Treatment of Pulmonary Hypertension

Joachim Mittendorf, Stefan Weigand, Cristina Alonso‐Alija et al. · ChemMedChem · 2009 · 182 citations

Medicine, Pharmacokinetics, Pharmacology +16

Enzyme‐Catalyzed Synthesis of 1‐Deoxymannojirimycin, 1‐Deoxynojirimycin, and 1,4‐Dideoxy‐1,4‐imino‐<scp>D</scp>‐arabinitol

Thomas Ziegler, Alexander Straub, Franz Effenberger · Angewandte Chemie International Edition in English · 1988 · 139 citations

Life Sciences, Biochemistry, Biocatalysis +16