Helicobacter pylori VacA-induced Inhibition of GSK3 through the PI3K/Akt Signaling Pathway

NF-κB is a target of AKT in anti-apoptotic PDGF signalling

Julia A. Romashkova, Sergei S. Makarov · Nature · 1999 · 1.8K citations

Signaling Pathway, Receptor Tyrosine Kinase, Immunology +7

Requirement for glycogen synthase kinase-3β in cell survival and NF-κB activation

Klaus P. Hoeflich, Juan Luo, Elizabeth A. Rubie et al. · Nature · 2000 · 1.4K citations

Signal Transduction, Signaling Pathway, Molecular Pathway +11

Gene structure of the Helicobacter pylori cytotoxin and evidence of its key role in gastric disease.

John L. Telford, P Ghiara, M. Dell’Orco et al. · The Journal of Experimental Medicine · 1994 · 591 citations

Microbial Toxin, Dysbiosis, Helicobacter Pylori Cytotoxin +15

β-catenin–sensitive isoforms of lymphoid enhancer factor-1 are selectively expressed in colon cancer

Karine Hovanes, Tony W.H. Li, Jesus E. Munguia et al. · Nature Genetics · 2001 · 463 citations

Tumor Biology, Gastrointestinal Oncology, Medicine +11

Helicobacter pylori CagA interacts with E-cadherin and deregulates the β-catenin signal that promotes intestinal transdifferentiation in gastric epithelial cells

Yo Kurashima, Yasuhiro Teishikata, Yukie Yamahashi et al. · Oncogene · 2007 · 455 citations · Full text

Signal Transduction, Gastrointestinal Pharmacology, β-Catenin Signal +10