Takeshi Azuma

SHP-2 Tyrosine Phosphatase as an Intracellular Target of <i>Helicobacter pylori</i> CagA Protein

Hideaki Higashi, Ryouhei Tsutsumi, Syuichi Muto et al. · Science · 2002 · 1K citations

Life Sciences, Biochemistry, Molecular Biology +17

Transgenic expression of <i>Helicobacter pylori</i> CagA induces gastrointestinal and hematopoietic neoplasms in mouse

Naomi Ohnishi, Hitomi Yuasa, Shinya Tanaka et al. · Proceedings of the National Academy of Sciences · 2008 · 585 citations · Full text

Medicine, Molecular Biology, Oncology +17

Biological activity of the <i>Helicobacter pylori</i> virulence factor CagA is determined by variation in the tyrosine phosphorylation sites

Hideaki Higashi, Ryouhei Tsutsumi, Akiko Fujita et al. · Proceedings of the National Academy of Sciences · 2002 · 574 citations

Life Sciences, Microbiology, Molecular Biology +17

B7-H1 is a ubiquitous antiapoptotic receptor on cancer cells

Takeshi Azuma, Sheng Yao, Gefeng Zhu et al. · Blood · 2008 · 541 citations · Full text

Life Sciences, Cancer Biology, Oncology +8

Helicobacter pylori CagA targets PAR1/MARK kinase to disrupt epithelial cell polarity

Iraj Saadat, Hideaki Higashi, Chikashi Obuse et al. · Nature · 2007 · 489 citations

Life Sciences, Microbiology, Molecular Biology +14