Defective proteolytic systems in Mybpc3-targeted mice with cardiac hypertrophy

Autophagy in the Pathogenesis of Disease

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Cell Autophagy, Mitophagy, Autoimmune Disease +10

Autophagy fights disease through cellular self-digestion

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Cell Autophagy, Mitophagy, Autoimmune Disease +8

p62/SQSTM1 Binds Directly to Atg8/LC3 to Facilitate Degradation of Ubiquitinated Protein Aggregates by Autophagy

Serhiy Pankiv, Terje Høyvarde Clausen, Trond Lamark et al. · Journal of Biological Chemistry · 2007 · 4.5K citations · Full text

Mitophagy, Facilitate Degradation, Molecular Biology +20

Inhibitors of the proteasome block the degradation of most cell proteins and the generation of peptides presented on MHC class I molecules

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Proteasome Block, Biochemistry, Mhc Class +13

The ubiquitinproteasome pathway is required for processing the NF-κB1 precursor protein and the activation of NF-κB

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