Concepedia

Pyridopyrimidinone inhibitors of HIV-1 RNase H

Emile J. Velthuisen, Brian A. Johns, Peter Gerondelis, Yan Chen, Ming Li, Ke Mou, Wenwen Zhang, John W. Seal, Kendra E. Hightower, Sónia Miranda,

European Journal of Medicinal Chemistry · 2014 · 17 citations · 18 references

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18

Physiochemical drug properties associated with in vivo toxicological outcomes

Jason D. Hughes, Julian Blagg, David A. Price et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 973 citations

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Retroviral intasome assembly and inhibition of DNA strand transfer

S. Hare, Saumya Gupta, Eugene Valkov et al. · Nature · 2010 · 666 citations · Full text

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A naphthyridine carboxamide provides evidence for discordant resistance between mechanistically identical inhibitors of HIV-1 integrase

Daria J. Hazuda, Neville J. Anthony, Robert Gomez et al. · Proceedings of the National Academy of Sciences · 2004 · 333 citations · Full text

, , +17

Molecular mechanisms of retroviral integrase inhibition and the evolution of viral resistance

S. Hare, Ann Vos, R. Clayton et al. · Proceedings of the National Academy of Sciences · 2010 · 303 citations · Full text

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Structural and Functional Analyses of the Second-Generation Integrase Strand Transfer Inhibitor Dolutegravir (S/GSK1349572)

S. Hare, Steven J. Smith, Mathieu Métifiot et al. · Molecular Pharmacology · 2011 · 258 citations · Full text

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