[3H]-Methoxymethyl-MTEP and [3H]-Methoxy-PEPy: potent and selective radioligands for the metabotropic glutamate subtype 5 (mGlu5) receptor

Reinforcing and locomotor stimulant effects of cocaine are absent in mGluR5 null mutant mice

Cristiano Chiamulera, Mark P. Epping-Jordan, Alessandro Zocchi et al. · Nature Neuroscience · 2001 · 549 citations

Life Sciences, Neurobiology, Neuroscience +14

Potential anxiolytic‐ and antidepressant‐like effects of MPEP, a potent, selective and systemically active mGlu5 receptor antagonist

E Tatarczyńska, Aleksandra Kłodzińska, E Chojnacka-Wójcik et al. · British Journal of Pharmacology · 2001 · 309 citations · Full text

Medicine, Neuroscience, Pharmacology +14

Anxiolytic-Like Effects of the Prototypical Metabotropic Glutamate Receptor 5 Antagonist 2-Methyl-6-(phenylethynyl)pyridine in Rodents

Will Spooren, A. Vassout, H.C. Neijt et al. · Journal of Pharmacology and Experimental Therapeutics · 2000 · 266 citations

Medicine, Neuroscience, Pharmacology +15

SIB-1757 and SIB-1893: Selective, Noncompetitive Antagonists of Metabotropic Glutamate Receptor Type 5

Mark A. Varney, Nicholas D. P. Cosford, Christine Jachec et al. · Journal of Pharmacology and Experimental Therapeutics · 1999 · 189 citations

Medicine, Neuroscience, Pharmacology +17

Anxiolytic-like activity of the mGluR5 antagonist MPEPA comparison with diazepam and buspirone

Jesse Brodkin, Chris S Busse, Stacey J. Sukoff Rizzo et al. · Pharmacology Biochemistry and Behavior · 2002 · 144 citations

Medicine, Pharmacology, Psychiatry +11