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Structure-based optimization of potent PDK1 inhibitors

Mauro Angiolini, Patrizia Banfi, Elena Casale, Francesco Casuscelli, Claudio Fiorelli, Maria Beatrice Saccardo, Marco Silvagni, Fabio Zuccotto

Bioorganic & Medicinal Chemistry Letters · 2010 · 29 citations · 13 references

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13

<i>Coot</i>: model-building tools for molecular graphics

Paul Emsley, Kevin Cowtan · Acta Crystallographica Section D Biological Crystallography · 2004 · 31.4K citations · Full text

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QXP: Powerful, rapid computer algorithms for structure-based drug design

Colin McMartin, Regine S. Bohacek · Journal of Computer-Aided Molecular Design · 1997 · 512 citations

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Novel Small Molecule Inhibitors of 3-Phosphoinositide-dependent Kinase-1

Richard I. Feldman, James M. Wu, Mark A. Polokoff et al. · Journal of Biological Chemistry · 2005 · 228 citations · Full text

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High resolution crystal structure of the human PDK1 catalytic domain defines the regulatory phosphopeptide docking site

Ricardo M. Biondi · The EMBO Journal · 2002 · 206 citations · Full text

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Pd‐Catalyzed N‐Arylation of Heteroarylamines.

Jingjun Yin, Matthew M. Zhao, Mark A. Huffman et al. · ChemInform · 2003 · 171 citations · Full text

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