Claudio Fiorelli

Discovery of Entrectinib: A New 3-Aminoindazole As a Potent Anaplastic Lymphoma Kinase (ALK), c-ros Oncogene 1 Kinase (ROS1), and Pan-Tropomyosin Receptor Kinases (Pan-TRKs) inhibitor

Maria Menichincheri, Elena Ardini, Paola Magnaghi et al. · Journal of Medicinal Chemistry · 2016 · 298 citations · Full text

Medicine, Oncology, Pharmacology +17

Kernel-Based, Partial Least Squares Quantitative Structure-Retention Relationship Model for UPLC Retention Time Prediction: A Useful Tool for Metabolite Identification

Federico Falchi, Sine Mandrup Bertozzi, Giuliana Ottonello et al. · Analytical Chemistry · 2016 · 50 citations

Life Sciences, Pharmaceutical Analysis, Drug Discovery +16

Synthesis and Structure–Activity Relationship (SAR) of 2-Methyl-4-oxo-3-oxetanylcarbamic Acid Esters, a Class of Potent <i>N</i>-Acylethanolamine Acid Amidase (NAAA) Inhibitors

Stefano Ponzano, Fabio Bertozzi, Luisa Mengatto et al. · Journal of Medicinal Chemistry · 2013 · 46 citations · Full text

Life Sciences, Biochemistry, Pharmacology +17

Asymmetric Synthesis of 2-(2-Pyridyl)aziridines from 2-Pyridineimines Bearing Stereogenic <i>N</i>-Alkyl Substituents and Regioselective Opening of the Aziridine Ring

Diego Savoia, Giuseppe Alvaro, Romano Di Fabio et al. · The Journal of Organic Chemistry · 2006 · 42 citations

Natural Sciences, Chemistry, Medicinal Chemistry +13

Discovery of NMS-E973 as novel, selective and potent inhibitor of heat shock protein 90 (Hsp90)

Maria Gabriella Brasca, Sergio Mantegani, Nadia Amboldi et al. · Bioorganic & Medicinal Chemistry · 2013 · 36 citations · Full text

Life Sciences, Medicinal Chemistry, Molecular Biology +4