A viable mouse model of factor X deficiency provides evidence for maternal transfer of factor X

HPRT-deficient (Lesch–Nyhan) mouse embryos derived from germline colonization by cultured cells

Martin Hooper, Kate Hardy, Alan H. Handyside et al. · Nature · 1987 · 1.2K citations

Life Sciences, Developmental Biology, Genetics +16

PTC124 targets genetic disorders caused by nonsense mutations

Ellen Welch, Elisabeth R. Barton, Jin Zhuo et al. · Nature · 2007 · 1.1K citations

Life Sciences, Genetics, Molecular Genetics +8

Factor Xa Induces Cytokine Production and Expression of Adhesion Molecules by Human Umbilical Vein Endothelial Cells

Nicole H. M. Senden, T M Jeunhomme, Johan W. M. Heemskerk et al. · The Journal of Immunology · 1998 · 190 citations · Full text

Life Sciences, Cell Biology, Immunology +17

Blood Coagulation Factor X Deficiency Causes Partial Embryonic Lethality and Fatal Neonatal Bleeding in Mice

Mieke Dewerchin, Lieve Moons, Peter Carmeliet et al. · Thrombosis and Haemostasis · 2000 · 175 citations

Life Sciences, Developmental Biology, Genetics +17

Regulatory elements in the introns of the human HPRT gene are necessary for its expression in embryonic stem cells.

Laura Reid, Ronald G. Gregg, O. Smithies et al. · Proceedings of the National Academy of Sciences · 1990 · 103 citations

Life Sciences, Genetics, Molecular Genetics +15