O. Smithies

Quantitative procedures for use with the Edman-Begg sequenator. Partial sequences of two unusual immunoglobulin light chains, Rzf and Sac

O. Smithies, D. M. Gibson, Ellen Fanning et al. · Biochemistry · 1971 · 679 citations

Immunohematology, Laboratory Immunology, Immunodeficiencies +18

Regulation of blood pressure by the type 1A angiotensin II receptor gene.

Masaki Ito, Michael I. Oliverio, Peter Mannon et al. · Proceedings of the National Academy of Sciences · 1995 · 605 citations · Full text

Hypertension, Genetics, Renal Inflammation +17

Single-copy transgenic mice with chosen-site integration.

Sarah K. Bronson, E. G. Plaehn, K D Kluckman et al. · Proceedings of the National Academy of Sciences · 1996 · 294 citations · Full text

Knockout Mouse, Developmental Biology, Xenotransplantation +14

Germ-line transmission of a planned alteration made in a hypoxanthine phosphoribosyltransferase gene by homologous recombination in embryonic stem cells.

Beverly H. Koller, Lora J. Hagemann, Thomas Doetschman et al. · Proceedings of the National Academy of Sciences · 1989 · 222 citations · Full text

Genetics, Molecular Genetics, Reproductive Biology +19

Recombinant fragment assay for gene targetting based on the polymerase chain reaction

H.-S. Kim, O. Smithies · Nucleic Acids Research · 1988 · 193 citations · Full text

Genetics, Molecular Biology, Molecular Genetics +18