Targeted mutation of the DNA methyltransferase gene results in embryonic lethality

En Li, Timothy H. Bestor, Rudolf Jaenisch

Cell

Developmental BiologyEmbryonic LethalityEpigenetic ChangeGeneticsDna Methylation +6

Mice carrying null mutations of the genes encoding insulin-like growth factor I (Igf-1) and type 1 IGF receptor (Igf1r)

Jeh-Ping Liu, Julie C. Baker, Archlbald S. Perkins, +2

Cell

Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

Philippe Soriano, Charles A. Montgomery, Robert S. Geske, +1

Cell

SclerostinDevelopmental BiologyBone Morphogenic ProteinCell SignalingC-src Proto-oncogene Leads +5

Alternative pathway of insulin signalling in mice with targeted disruption of the IRS-1 gene

Eiichi Araki, Myra A. Lipes, Mary‐Elizabeth Patti, +4

Nature

Molecular PhysiologySignal TransductionInsulin SignallingSignaling PathwayDiabetes +9

Insulin resistance and growth retardation in mice lacking insulin receptor substrate-1

Hiroyuki Tamemoto, Takashi Kadowaki, Kazuyuki Tobe, +15

Nature

Insulin ResistanceMetabolic SyndromeInsulin SignalingGrowth HormoneInsulin Receptor Substrate-1 +9

Role of IRS-2 in insulin and cytokine signalling

Xiao Jian Sun, Ling-Mei Wang, Yitao Zhang, +6

Nature

Molecular PhysiologySignal TransductionDiabetesCytokine SignallingMetabolic Regulation +4

Altered striatal function in a mutant mouse lacking D1A dopamine receptors.

John Drago, C R Gerfen, Jean E. Lachowicz, +7

Proceedings of the National Academy of Sciences

D1a Dopamine ReceptorsNeurotransmitterDopamine ReceptorsNeurotransmissionSocial Sciences +19

Binding of insulin receptors to lectins: evidence for common carbohydrate determinants on several membrane receptors

J A Hedo, Len C. Harrison, Jesse Roth

Biochemistry

Insulin ReceptorsGlycobiologyAltmetric Attention ScoreCommon Carbohydrate DeterminantsInsulin Signaling +16

Insulin-like growth factor I binding in hepatocytes from human liver, human hepatoma, and normal, regenerating, and fetal rat liver.

J F, John Poulos, Olivia Ittoop, +3

Journal of Clinical Investigation

Human GrowthImmunologyIgf-i Binding SitesInsulin SignalingFetal Rat Liver +20

The contribution of insulin-dependent and insulin-independent glucose uptake to intravenous glucose tolerance in healthy human subjects

Steven E. Kahn, Ronald L. Prigeon, D. K. McCulloch, +8

Diabetes

Insulin ResistanceMetabolic SyndromeObesityIntravenous Glucose ToleranceMedicine +10