Relationship of drug metabolizing enzyme genotype to plasma levels as well as myelotoxicity of cyclophosphamide in breast cancer patients

Global trends in breast cancer incidence and mortality 1973–1997

Michelle D. Althuis, Jaclyn M Dozier, William F. Anderson et al. · International Journal of Epidemiology · 2005 · 564 citations · Full text

Medicine, Oncology, Cancer Epidemiology +15

Development of a Substrate-Activity Based Approach To Identify the Major Human Liver P-450 Catalysts of Cyclophosphamide and Ifosfamide Activation Based on cDNA-Expressed Activities and Liver Microsomal P-450 Profiles

Partha Pratim Roy, L J Yu, Charles L. Crespi et al. · Drug Metabolism and Disposition · 1999 · 319 citations

Medicine, Biochemistry, Pharmacology +17

Subunit diversity and tissue distribution of human glutathione S-transferases: interpretations based on electrospray ionization-MS and peptide sequence-specific antisera

Jonathan D. Rowe, Edward Nieves, Irving Listowsky · Biochemical Journal · 1997 · 229 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Role of polymorphic human CYP2B6 in cyclophosphamide bioactivation

H-J Xie, Ümit Yaşar, S Lundgren et al. · The Pharmacogenomics Journal · 2003 · 215 citations

Medicine, Pharmacokinetics, Pharmacology +12

Molecular Cloning of a Novel Human Diacylglycerol Kinase Highly Selective for Arachidonate-containing Substrates

Wen Tang, Michaeline Bunting, Guy A. Zimmerman et al. · Journal of Biological Chemistry · 1996 · 210 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +17