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Pyrido pyrimidinones as selective agonists of the high affinity niacin receptor GPR109A: Optimization of in vitro activity

Jens‐Uwe Peters, Holger Kühne, Henrietta Dehmlow, Uwe Grether, Aurelia Conte, Dominik Hainzl, Cornelia Hertel, Nicole A. Kratochwil, Michael B. Otteneder, Robert Narquizian,

Bioorganic & Medicinal Chemistry Letters · 2010 · 14 citations · 21 references

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21

PUMA-G and HM74 are receptors for nicotinic acid and mediate its anti-lipolytic effect

Sorin Tunaru, Jukka Kero, Annette Schaub et al. · Nature Medicine · 2003 · 795 citations

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Influence of nicotinic acid on serum cholesterol in man

Rudolf Altschul, A. Hoffer, J. Stephen · Archives of Biochemistry and Biophysics · 1955 · 723 citations

, , +9

Molecular Identification of High and Low Affinity Receptors for Nicotinic Acid

Alan Wise, Steven M. Foord, Neil J. Fraser et al. · Journal of Biological Chemistry · 2003 · 541 citations · Full text

, , +17

GPR109A (PUMA-G/HM74A) mediates nicotinic acid–induced flushing

Zoltán Benyó, Andreas Gille, Jukka Kero et al. · Journal of Clinical Investigation · 2005 · 338 citations · Full text

, , +16

Molecular identification of nicotinic acid receptor

Takatoshi Soga, Masazumi Kamohara, Jun Takasaki et al. · Biochemical and Biophysical Research Communications · 2003 · 316 citations

, , +14