Inhibition of RANTES expression by indirubin in influenza virus-infected human bronchial epithelial cells

Isolation of biologically active ribonucleic acid from sources enriched in ribonuclease

John M. Chirgwin, Alan Przybyla, Raymond J. MacDonald et al. · Biochemistry · 1979 · 22.2K citations

Life Sciences, Biochemistry, Molecular Biology +9

Indirubin, the active constituent of a Chinese antileukaemia medicine, inhibits cyclin-dependent kinases

Ralph Hoessel, Sophie Leclerc, Jane Endicott et al. · Nature Cell Biology · 1999 · 814 citations

Medicine, Medicinal Chemistry, Pharmacology +13

Indirubins Inhibit Glycogen Synthase Kinase-3β and CDK5/P25, Two Protein Kinases Involved in Abnormal Tau Phosphorylation in Alzheimer's Disease

Sophie Leclerc, Matthieu Garnier, Ralph Hoessel et al. · Journal of Biological Chemistry · 2001 · 723 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +13

Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways

Helmut Holtmann, Reinhard Winzen, Pamela M. Holland et al. · Molecular and Cellular Biology · 1999 · 295 citations

Life Sciences, Immunology, Molecular Biology +17

Inhibition of cyclin-dependent kinase 1 (CDK1) by indirubin derivatives in human tumour cells

Doris Marko, Silvia Schätzle, Anna Maria Friedel et al. · British Journal of Cancer · 2001 · 200 citations · Full text

Medicine, Oncology, Pharmacology +13