Helmut Holtmann

Targeted Disruption of the Mouse Caspase 8 Gene Ablates Cell Death Induction by the TNF Receptors, Fas/Apo1, and DR3 and Is Lethal Prenatally

Eugene Varfolomeev, Marcus Schuchmann, Victor Luria et al. · Immunity · 1998 · 1.2K citations · Full text

Inflammation, Knockout Mouse, Signal Transduction +12

Multiple control of interleukin-8 gene expression

Elke Hoffmann, Oliver Dittrich‐Breiholz, Helmut Holtmann et al. · Journal of Leukocyte Biology · 2002 · 1K citations

MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels

Armin Neininger, Dimitris L. Kontoyiannis, Alexey Kotlyarov et al. · Journal of Biological Chemistry · 2002 · 389 citations · Full text

Antibodies to a soluble form of a tumor necrosis factor (TNF) receptor have TNF-like activity.

Hartmut Engelmann, Helmut Holtmann, Cord Brakebusch et al. · Journal of Biological Chemistry · 1990 · 384 citations · Full text

Immunology, Immune Regulation, Pathology +17

Soluble forms of tumor necrosis factor receptors (TNF-Rs). The cDNA for the type I TNF-R, cloned using amino acid sequence data of its soluble form, encodes both the cell surface and a soluble form of the receptor.

Y. Nophar, O. Kemper, Cord Brakebusch et al. · The EMBO Journal · 1990 · 332 citations · Full text

Inflammation, Soluble Form, Immunology +8