Reinhard Winzen

The p38 MAP kinase pathway signals for cytokine-induced mRNA stabilization via MAP kinase-activated protein kinase 2 and an AU-rich region-targeted mechanism

Reinhard Winzen · The EMBO Journal · 1999 · 773 citations · Full text

Signal Transduction, Signaling Pathway, Au-rich Region-targeted Mechanism +9

MK2 Targets AU-rich Elements and Regulates Biosynthesis of Tumor Necrosis Factor and Interleukin-6 Independently at Different Post-transcriptional Levels

Armin Neininger, Dimitris L. Kontoyiannis, Alexey Kotlyarov et al. · Journal of Biological Chemistry · 2002 · 389 citations · Full text

Induction of Interleukin-8 Synthesis Integrates Effects on Transcription and mRNA Degradation from at Least Three Different Cytokine- or Stress-Activated Signal Transduction Pathways

Helmut Holtmann, Reinhard Winzen, Pamela M. Holland et al. · Molecular and Cellular Biology · 1999 · 295 citations · Full text

Functional Analysis of KSRP Interaction with the AU-Rich Element of Interleukin-8 and Identification of Inflammatory mRNA Targets

Reinhard Winzen, Basant Kumar Thakur, Oliver Dittrich‐Breiholz et al. · Molecular and Cellular Biology · 2007 · 141 citations

Immune Regulation, Immunology, Innate Immunity +21

Distinct Domains of AU-Rich Elements Exert Different Functions in mRNA Destabilization and Stabilization by p38 Mitogen-Activated Protein Kinase or HuR

Reinhard Winzen, Gayatri Gowrishankar, Frank Bollig et al. · Molecular and Cellular Biology · 2004 · 125 citations · Full text

Immunology, Molecular Biology, Mrna Destabilization +18