Development of predictive pharmacokinetic simulation models for drug discovery

A Theoretical Basis for a Biopharmaceutic Drug Classification: The Correlation of in Vitro Drug Product Dissolution and in Vivo Bioavailability

Gordon L. Amidon, Hans Lennernäs, Vinod P. Shah et al. · Pharmaceutical Research · 1995 · 5.3K citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +16

Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells

Per Artursson, Johan Karlsson · Biochemical and Biophysical Research Communications · 1991 · 1.9K citations

Pharmacy, Pharmacokinetics, Pharmacology +16

Managing the drug discovery/development interface

Tony Kennedy · Drug Discovery Today · 1997 · 522 citations

Pharmacy, Medicinal Chemistry, Drug Design +10

Pharmaceutical innovation by the seven UK‐owned pharmaceutical companies (1964‐1985).

RA Prentis, Y. Lis, SR Walker · British Journal of Clinical Pharmacology · 1988 · 473 citations · Full text

Pharmacy, Pharmacology, Biopharmaceutics +6

9-(1,3-Dihydroxy-2-propoxymethyl)guanine: a new potent and selective antiherpes agent

John Martin, Charles A. Dvorak, Donald F. Smee et al. · Journal of Medicinal Chemistry · 1983 · 340 citations

Medicine, Medicinal Chemistry, Pharmacology +5