Concepedia

Direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes via Pd/Cu-catalyzed phosphonium coupling

Fu‐An Kang, James C. Lanter, Chaozhong Cai, Zhihua Sui, William V. Murray

Chemical Communications · 2010 · 66 citations · 16 references

DOI

Concepts

Abstract

The first chemoselective direct dehydrative cross-coupling of tautomerizable heterocycles with alkynes has been achieved via C-H/C-OH bond activations with direct C(sp(2))-C(sp) bond formation, which is in line with ideal synthesis using readily available materials.

References

16

Cross-Dehydrogenative Coupling (CDC): Exploring C−C Bond Formations beyond Functional Group Transformations

Chao‐Jun Li · Accounts of Chemical Research · 2008 · 2.8K citations

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David R. Stuart, Keith Fagnou · Science · 2007 · 1K citations

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Palladium-Catalyzed Alkylation of sp<sup>2</sup> and sp<sup>3</sup> C−H Bonds with Methylboroxine and Alkylboronic Acids:  Two Distinct C−H Activation Pathways

Xiao Chen, Charles E. Goodhue, Jin‐Quan Yu · Journal of the American Chemical Society · 2006 · 535 citations

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Bi‐Jie Li, Shiliang Tian, Fang Zhao et al. · Angewandte Chemie International Edition · 2007 · 483 citations

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Palladium‐Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids

Shang‐Dong Yang, Chang‐Liang Sun, Fang Zhao et al. · Angewandte Chemie International Edition · 2008 · 444 citations

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