Chaozhong Cai

Asymmetric synthesis of novel highly sterically constrained (2S,3S)-3-methyl-3-trifluoromethyl- and (2S,3S,4R)-3-trifluoromethyl-4-methylpyroglutamic acids

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby et al. · Tetrahedron · 1999 · 105 citations

Engineering, Asymmetric Synthesis, Fluorous Synthesis +6

(<i>S</i>)- or (<i>R</i>)-3-(<i>E</i>-Enoyl)-4-phenyl-1,3- oxazolidin-2-ones:  Ideal Michael Acceptors To Afford a Virtually Complete Control of Simple and Face Diastereoselectivity in Addition Reactions with Glycine Derivatives

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby · Organic Letters · 2000 · 87 citations

Stereochemically defined C-substituted glutamic acids and their derivatives. 1. An efficient asymmetric synthesis of (2S,3S)-3-methyl- and -3-trifluoromethylpyroglutamic acids

Vadim A. Soloshonok, Chaozhong Cai, Victor J. Hruby et al. · Tetrahedron · 1999 · 86 citations

Derivatives, Bioorganic Chemistry, Biochemistry +11

Michael Addition Reactions between Chiral Equivalents of a Nucleophilic Glycine and (<i>S</i>)- or (<i>R</i>)-3-[(<i>E</i>)-Enoyl]-4-phenyl-1,3-oxazolidin-2-ones as a General Method for Efficient Preparation of β-Substituted Pyroglutamic Acids. Case of Topographically Controlled Stereoselectivity

Vadim A. Soloshonok, Chaozhong Cai, Takeshi Yamada et al. · Journal of the American Chemical Society · 2005 · 86 citations · Full text

Virtually Complete Control of Simple and Face Diastereoselectivity in the Michael Addition Reactions between Achiral Equivalents of a Nucleophilic Glycine and (<i>S</i>)- or (<i>R</i>)-3-(<i>E</i>-Enoyl)-4-phenyl-1,3-oxazolidin-2-ones:  Practical Method for Preparation of β-Substituted Pyroglutamic Acids and Prolines

Vadim A. Soloshonok, Hisanori Ueki, Rohit Tiwari et al. · The Journal of Organic Chemistry · 2004 · 86 citations