Multiple CH Activations To Construct Biologically Active Molecules in a Process Completely Free of Organohalogen and Organometallic Components

Abstract

Step by step: Highly selective cross dehydrogenative arylation of acetanilides was developed to construct biaryls under mild condition. With this method, different aryl CH bonds were activated in sequential reactions to construct functionalized carbazoles (see scheme), which are present as key structural units in various biological molecules and organic optical materials.