Concepedia

NADP+-dependent IDH1R132 mutation and its relevance for glioma patient survival

Nishita M.S. Baldewpersad Tewarie, Ilsa A. V. Burgers, Yousif Dawood, Hannah Boon, Melina G.H.E. den Brok, Jet H. Klunder, Kristijn B. Koopmans, Emma Rademaker, Hans B. van den Broek, Sil M. van den Bersselaar,

Medical Hypotheses · 2013 · 31 citations · 36 references

DOI

Concepts

References

36

<i>IDH1</i>and<i>IDH2</i>Mutations in Gliomas

Hai Yan, D. Williams Parsons, Genglin Jin et al. · New England Journal of Medicine · 2009 · 5.9K citations · Full text

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Cancer-associated IDH1 mutations produce 2-hydroxyglutarate

Lenny Dang, David W. White, Bryson D. Bennett et al. · Nature · 2009 · 4.1K citations · Full text

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Oncometabolite 2-Hydroxyglutarate Is a Competitive Inhibitor of α-Ketoglutarate-Dependent Dioxygenases

Wei Xu, Hui Yang, Ying Liu et al. · Cancer Cell · 2011 · 2.8K citations · Full text

, , +8

Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt

Henryk Dudek, Sandeep Robert Datta, Thomas Franke et al. · Science · 1997 · 2.5K citations

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Recurring Mutations Found by Sequencing an Acute Myeloid Leukemia Genome

Elaine R. Mardis, Li Ding, David J. Dooling et al. · New England Journal of Medicine · 2009 · 2.2K citations · Full text

, , +17