Potent P2Y1 urea antagonists bearing various cyclic amine scaffolds

MRS2500 [2-Iodo-N6-methyl-(N)-methanocarba-2′-deoxyadenosine-3′,5′-bisphosphate], a Potent, Selective, and Stable Antagonist of the Platelet P2Y1 Receptor with Strong Antithrombotic Activity in Mice

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Medicine, Medicinal Chemistry, Pharmacology +17

P2 receptors and platelet function

Béatrice Hechler, Christian Gachet · Purinergic Signalling · 2011 · 133 citations · Full text

Medicine, Pharmacology, Physiology +14

Risk Stratification of Patients With Acute Anterior Myocardial Infarction and Right Bundle-Branch Block

Cheuk‐Kit Wong, Wanzhen Gao, Ralph Stewart et al. · Circulation · 2006 · 66 citations

Medicine, Cardiology, Internal Medicine +16

Discovery of 2-(Phenoxypyridine)-3-phenylureas as Small Molecule P2Y₁ Antagonists

Hannguang J. Chao, Huji Turdi, Timothy F. Herpin et al. · Journal of Medicinal Chemistry · 2013 · 64 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +17

P2Y1 receptor antagonists as novel antithrombotic agents

Jeffrey A. Pfefferkorn, Chulho Choi, Thomas Winters et al. · Bioorganic & Medicinal Chemistry Letters · 2008 · 51 citations · Full text

Medicine, Pharmacology, Pharmacotherapy +12